The report results are based on the ClinVar (https://www.ncbi.nlm.nih.gov/clinvar/) clinical genetic testing database provided by the National Center for Bioinformatics. We use this database to evaluate together with Insight’s proprietary program analysis. Gene variation and disease-causing risk index correlate with genotype and disease risk. In addition, it is also supported by the GENOME-WIDE ASSOCIATION STUDY (GWAS), which lists the gene loci related to diseases or traits and the genes that cause abnormal biosynthesis of proteins in the body. As the evidence supports the particular gene, the higher the gene mutations, the higher the disease occurs.
Total Guardian Cancer | Gene detection of cardiovascular and neurodegenerative diseases evaluated 34,286 related SNPs to detection of 29 types of cancer: Lung cancer| Liver cancer| Colorectal cancer| Breast cancer| Oral cancer| Prostate cancer| Stomach cancer| Pancreatic cancer| Esophageal cancer| Ovarian cancer| Cervical cancer| Endometrial cancer| Chronic lymphocytic leukemia| Acute myeloid leukemia| Chronic myeloid leukemia| Non-Hodgkin’s lymphoma| Multiple myeloma| Nasopharyngeal carcinoma Head and neck cancer| Thyroid cancer| Bladder cancer| Basal cell carcinoma| Melanoma| Testicular cancer| Renal cell carcinoma| Glioma| Meningiomas| Hodgkin's lymphoma| Chondrosarcoma.
 
Detection of 37 cardiovascular diseases: Atrial septal defect | Familial dilated cardiomyopathy | Familial hypertrophic cardiomyopathy | Long QT syndrome | Short QT syndrome | AnkyrinB syndrome | Familial atrial fibrillation | Family Heart Block | Arrhythmogenic Right Ventricular Myocardial Disease | Ventricular Fibrillation | Sinus Syndrome | Brugada Syndrome | Wolff-Parkinson-White Syndrome | Catecholamine-Sensitive Polymorphic Ventricular Pulse | Stroke | Myocardial Infarction | Artery Atherosclerosis| Essential hypertension| Familial migraine| Coronary artery calcification| Coronary artery disease| Pulmonary hypertension| Thoracic aortic aneurysm| Thrombosis-prone disease| Pulmonary vein occlusive disease| Upper valve aortic valve stenosis| Hairy Cerebrovascular disease | Fabry disease | Gestational diabetes | Type 2 diabetes | Familial HDL deficiency | Familial hypercholesterolemia | Familial hypertriglyceridemia | Sitosterolemia | Hereditary folate malabsorption | Periodic paralysis of thyroid toxicity | Congenital hypothyroidism.
 
Detection of 10 neurodegenerative diseases: Progressive supranuclear palsy | Frontotemporal dementia | Dementia with Lewy body | Alzheimer's disease | Late-stage Alzheimer's disease | Parkinson's disease | Huntington's disease | NOTCH3 gene abnormality Stroke and Vascular Dementia | Multiple System Degeneration | Amyotrophic Lateral Sclerosis