The report results are based on the ClinVar (https://www.ncbi.nlm.nih.gov/clinvar/) clinical genetic testing database provided by the National Center for Bioinformatics. We use this database to evaluate together with Insight’s proprietary program analysis. Gene variation and disease-causing risk index correlate with genotype and disease risk. In addition, it is also supported by the GENOME-WIDE ASSOCIATION STUDY (GWAS), which lists the gene loci related to diseases or traits and the genes that cause abnormal biosynthesis of proteins in the body. As the evidence supports the particular gene, the higher the gene mutations, the higher the disease occurs. 
 
The cardiovascular and neurodegenerative disease genetic test evaluated 10,843 related SNPs to detect 37 cardiovascular diseases: atrial septal defect | familial dilated cardiomyopathy | familial hypertrophic cardiomyopathy | long QT syndrome | short QT syndrome | AnkyrinB syndrome | familial atrial fibrillation | familial heart block | arrhythmogenic right ventricular cardiomyopathy | ventricular fibrillation | sick sinus syndrome | White's syndrome | Catecholamine sensitive polymorphic ventricular pulse | Stroke | Myocardial infarction | Atherosclerosis | Primary hypertension | Familial migraine | Coronary artery calcification | Coronary artery disease | Pulmonary hypertension | Tumors | Thrombosis-prone diseases | Pulmonary venous occlusive diseases | Upper valve aortic valve stenosis | Hairy cerebrovascular disease | Fabry disease | Gestational diabetes | Type 2 diabetes | Familial HDL deficiency | Syndrome | Familial hypertriglyceridemia | Sitosterolemia | Hereditary folate malabsorption | Periodic paralysis of thyroid toxicity | Congenital hypothyroidism.
 
Detection of 9 neurodegenerative diseases: Progressive supranuclear palsy | Frontotemporal dementia | Dementia with Lewy body | Alzheimer's disease | Parkinson's disease | Huntington's disease | NOTCH3 gene abnormality Stroke and Vascular Dementia | Multiple System Degeneration | Amyotrophic Lateral Sclerosis