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Testing itemsPolycystic kidney disease | Hypertrophic heart disease Test contentWhat is polycystic kidney disease?Polycystic kidney disease is a widespread genetic disease in cats that can cause kidney disease and progressive kidney failure. About 6% of cats worldwide suffer from polycystic kidney disease. Polycystic kidney disease is the presence of a defective gene that promotes the kidney's normal development and structural integrity. Cat genetic testing will provide invaluable insights into the risk of genetic diseases for your cat's health management in advance. What is hypertrophic heart disease?Hypertrophic cardiomyopathy is the most diagnosed cardiac disease in cats. The defect gene causes increased ventricular myocardium thickness. Therefore, cats are at risk of heart failure, thromboembolism, or occasional sudden death.  Genetic testing for hypertrophic heart disease can help breeders identify the risk of genetic disease and make the proper matching selection based on the genetic conditions to reduce the risk of affected offspring. SuitablePolycystic kidney diseaseCat Breeds at High Risk: Persian, American Shorthair, Exotic ShorthairCat breeds with moderate risk: Asian, Bombay, Pomeranian, Snowshoe, Ragdoll, Birman, German Regal, Cornish Rex ็็Hypertrophic heart diseaseMaine Coon, Ragdoll, Shorthair, or related breeds derived from these breeds

Testing itemsPolycystic kidney disease | Hypertrophic heart disease | Pyruvate kinase deficiency | Progressive retinal atrophy Test contentWhat is polycystic kidney disease?Polycystic kidney disease is a widespread genetic disease in cats that can cause kidney disease and progressive kidney failure. About 6% of cats worldwide suffer from polycystic kidney disease. Polycystic kidney disease is the presence of a defective gene that promotes the kidney's normal development and structural integrity. Cat genetic testing will provide invaluable insights into the risk of genetic diseases for your cat's health management in advance. What is hypertrophic heart disease?Hypertrophic cardiomyopathy is the most diagnosed cardiac disease in cats. The defect gene causes increased ventricular myocardium thickness. Therefore, cats are at risk of heart failure, thromboembolism, or occasional sudden death.  Genetic testing for hypertrophic heart disease can help breeders identify the risk of genetic disease and make the proper matching selection based on the genetic conditions to reduce the risk of affected offspring. SuitablePolycystic kidney diseaseCat Breeds at High Risk: Persian, American Shorthair, Exotic ShorthairCat breeds with moderate risk: Asian, Bombay, Pomeranian, Snowshoe, Ragdoll, Birman, German Regal, Cornish Rex Hypertrophic heart diseaseMaine Coon, Ragdoll, Shorthair, or related breeds derived from these breeds Pyruvate Kinase Deficiency (PK Deficiency)Pyruvate kinase is an enzyme found in red blood cells. Pyruvate kinase deficiency is an inherited disorder when red blood cells break down faster than they should, resulting in a reduced number of red blood cells and anemia.Common breeds are more affected in Abyssinian and Somali breeds, as well as random-bred domestic shorthair cats.        Many symptoms of Pyruvate kinase deficiency are from anemia with mild symptoms such as lethargy, weakness, and loss of appetite. Furthermore, also develop into acute anemia, which is life-threatening.  Progressive retinal atrophy    Progressive retinal atrophy is an inherited disease. It describes when the retina's photoreceptor cells (rods, cones) underdevelop or develop into retinal degeneration and atrophy. The cat's vision declines gradually, causing a risk of blindness. When the cat's vision is severely impaired, it may lose its direction or easily bump into objects.    The prevalence often occurs in the Abyssinian and Somani breeds, with other influences such as Oxycat, American Curly, Bengal, etc.

Test itemsbrown gene | dilute geneTest Gene DescriptionThe brown gene controls the synthesis of eumelanin. Mutations in the brown gene may change the content of eumelanin and thus affect the appearance of coat color. Two mutation sites have been found on the brown gene to affect the appearance of coat color. The allele b corresponds to chocolate color , and the allele bl corresponds to cinnamon, the inheritance pattern is basically recessive, but B is dominant relative to b and b is dominant relative to bl (B > b > bl), so as long as there is one allele that is B coat color would be black, but with one allele b and one bl, it would be chocolate.The dilution gene is related to the transport of melanin bodies, so when the dilution gene mutations may cause the melanosomes to not be transported to their destinations correctly, resulting in uneven distribution of pigment in the hair, a mutation site has been found in the dilution gene that leads to lighter hair color , the genetic mode is recessive inheritance, that is, two alleles d at the same time will have the performance of dilution.Detection speciesBritish Shorthair, Ragdoll, Munchkin, British Longhair, Norwegian Forest, Russian Blue, Maine Coon, and others are also common.